NYSE: SFE

2:41 PM ET 2/22/2012

PRICE

17.96

CHANGE

-0.1

52wk Range

13.02 - 21.35

Overview

Safeguard Scientifics deploys capital in entrepreneurial growth-stage life sciences and technology companies. Safeguard’s partner companies tend to address five general strategic themes — Maturity, Migration, Convergence, Compliance and Cost Containment — which tend to drive growth and attract entrepreneurs who need capital, operational support and strategic guidance.

Safeguard’s ability to provide both growth capital and strategic and operational guidance translates into significant competitive advantages for our partner companies. Our management team includes C-level executives who have been in the entrepreneur’s seat before and understand the challenges companies face at this stage.

In life sciences, Safeguard targets high-value areas of Molecular and Point-of-Care Diagnostics, Medical Devices, Regenerative Medicine, Specialty Pharmaceuticals and selected healthcare services, which represent lower regulatory risk and near-term revenue. Our current partner companies include:

• Alverix, Inc.
• Good Start Genetics, Inc.
• Medivo, Inc.
• NovaSom, Inc.
• NuPathe Inc. (Nasdaq: PATH)
• PixelOptics, Inc.
• Putney, Inc.

In technology, Safeguard targets recurring revenue companies in Internet / New Media, Financial Services IT, Healthcare IT and selected business services, which share a “transaction enabling” thesis and are near cash-flow position. Our current partner companies include:

• AdvantEdge Healthcare Solutions, Inc.
• Beyond.com, Inc.
• Bridgevine, Inc.
• Crimson Informatics, Inc.
• Hoopla Software, Inc.
• MediaMath, Inc.
• Spongecell, Inc.
• Swap.com, Inc.
• ThingWorx, Inc.

We believe this diversified strategy exploits the growth and counter-cyclicality of these sectors, providing investors with the opportunity to realize value more consistently compared with funds focused primarily on one sector. Safeguard has proven that building market-leaders demands a clear operational focus and a patient capital approach. The continued success of our partner companies proves that Safeguard's vision is being realized.