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safeguard partner company success stories

Great companies, realized.

We’re spotlighting the most recent Safeguard partner company success stories.

While Safeguard has fostered numerous industry leaders throughout our history, some of our most impactful successes have come within the last few years.

In December of 2010, Safeguard experienced the largest cash return in our history with GE Healthcare’s acquisition of Clarient. From there, we had three more successful exit transactions with the acquisition of Avid Radiopharmaceuticals, Advanced BioHealing and Portico Systems, which yielded a range of 3x to 13x cash-on-cash returns totaling $300+M in capital.

We are proud to have worked with each of these partner companies to build their businesses and expand their market opportunities. For more insight on how Safeguard helped position each of these companies for success, check out the following case studies:

  • Advanced BioHealing – Acquired by Shire (LSE:SHP) in 2011 for 13x Cash-on-Cash Return
  • Avid Radiopharmaceuticals – Acquired by Eli Lilly (NYSE:LLY) in 2010 for 3x Cash-on-Cash Return*,**
  • Clarient – Acquired by GE Healthcare in 2010 for 5x Increase in Market Cap* Since Repositioning
  • Portico Systems – Acquired by McKesson (NYSE:MCK) in 2011 for 4x Cash-on-Cash Return*


  • *Includes amounts currently held in escrow.
    **Return potential could approach 8x based on difficult revenue milestones.